The Bible teaches that God is the Creator of all things (Genesis 1:1), existing before and apart from His creation. Scripture affirms God's unchanging nature (Malachi 3:6) and His sovereignty over all creation (Colossians 1:16–17). The Bible emphasizes God's transcendence (Isaiah 55:8–9) while also acknowledging His immanence (Psalm 139:7–10). It calls for exclusive worship of God (Exodus 20:3–5), which contradicts panentheistic ideas that blur the lines between Creator and creation. The biblical view of God as perfect, self-existent, and distinct from creation stands in contrast to panentheism's concept of a God who encompasses and is affected by the universe.
The Creator/creation distinction in Scripture maintains God's transcendence while acknowledging His intimate involvement with creation. Creation can be admired as His handiwork, but not as an extension of His being. Creation can be valued and stewarded well, and we can trust in God’s constancy and faithfulness, rather than viewing Him as subject to the fluctuations of the universe. While the natural world may be subject to change, decay, and unpredictability, God remains unchanging, trustworthy, and not bound by the laws of the universe He created (Malachi 3:6). This allows us to place our ultimate trust in Him, knowing that His purposes and character do not shift with the changing tides of the cosmos. Through this understanding, we can live in awe of both God's majesty and His nearness, without confusing His essence with the material world He governs.