Seth, Adam and Eve's son born after Abel's death, is significant as the ancestor of the righteous line leading to Noah and Abraham and ultimately to Jesus. His lineage is notable for the beginning of people calling upon the name of the Lord, indicating a turn towards righteousness. The New Testament traces Jesus' genealogy back to Seth, highlighting God's fulfillment of the promise of a Savior through Seth's line. This lineage brought hope to Adam and Eve, and believers today live in faith and hope, awaiting the ultimate defeat of the serpent as promised in scripture.
Cain's murder of Abel demonstrated the quick escalation and utter devastation of sin. Seth's birth brought Adam and Eve hope. Seth's birth reminds us of God's faithfulness to set apart a people to Himself and to fulfill His plan of rescue for humanity. Through Seth's line, Jesus, whose blood speaks a better word than Abel's (Hebrews 12:24), was born. Paul explains, "The sting of death is sin, and the power of sin is the law. But thanks be to God, who gives us the victory through our Lord Jesus Christ" (1 Corinthians 15:56–57). Jesus is fully God and fully human. He lived a perfect life and died on the cross as payment for our sins. He rose back to life, proving He is who He claimed and that His sacrifice is sufficient. He is victorious over sin and death. All who put their faith in Him are forgiven by God and given eternal life (Ephesians 1:3–14; 2:1–10).
Adam and Eve had good reason to be hopeful when Seth was born. The Savior would, indeed, come. One day the serpent will be fully and finally crushed (Revelation 20:7–10). We know that, "The Lord is not slow to fulfill his promise as some count slowness, but is patient toward you, not wishing that any should perish, but that all should reach repentance" (2 Peter 3:9). So we live in faith, hope, and obedience. Like those in Enosh's time, we call upon the name of the Lord, knowing He is faithful and worthy of all praise.